Title:
• Gray → NMD (RNA likely degraded)
• Red → Pathogenic variants
NMD escape types:
• NMDER1: start-proximal (≤150 nt from start codon)
• NMDER2*: long exon (>400 nt from splice donor) • NMDER3*: distal (last exon / final 50 nt). Frameshifts in NMDER2/3 often yield stable truncated peptides, Use NMDEscape filter to exclude NMD & ER1.